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Test ID LH Luteinizing Hormone (LH), Serum

Useful For

An adjunct in the evaluation of menstrual irregularities

 

Evaluating patients with suspected hypogonadism

 

Predicting ovulation

 

Evaluating infertility

 

Diagnosing pituitary disorders

Method Name

Immunoenzymatic Assay 

Reporting Name

Luteinizing Hormone (LH), S

Specimen Type

Serum

Specimen Required

Container/Tube: 

Preferred: Serum gel

Acceptable: Red top

Specimen Volume: 0.6 mL

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 7 days
  Frozen  7 days

Reference Values

Males

0-14 days: not established

15 days-10 years: 0.3-2.8 IU/L

11 years: 0.3-1.8 IU/L

12 years: 0.3-4.0 IU/L

13 years: 0.3-6.0 IU/L

14 years: 0.5-7.9 IU/L

15-16 years: 0.5-10.8 IU/L

17 years: 0.9-5.9 IU/L

≥18 years: 1.8-8.6 IU/L

 

TANNER STAGES*

Stage l: 0.3-2.7 IU/L

Stage ll: 0.3-5.1 IU/L

Stage lll: 0.3-6.9 IU/L

Stage lV: 0.5-5.3 IU/L

Stage V: 0.8-11.8 IU/L

*Puberty onset occurs for boys at a median age of 11.5 (± 2) years. For boys there is no proven relationship between puberty onset and body weight or ethnic origin. Progression through Tanner stages is variable. Tanner stage V (adult) should be reached by age 18.

Females

0-14 days: not established

15 days-3 years: 0.3-2.5 IU/L

4-6 years: ≤1.9 IU/L

7-8 years: ≤3.0 IU/L

9-10 years: ≤4.0 IU/L

11 years: ≤6.5 IU/L

12 years: 0.4-9.9 IU/L

13 years: 0.3-5.4 IU/L

14 years: 0.5-31.2 IU/L

15 years: 0.5-20.7 IU/L

16 years: 0.4-29.4 IU/L

17 years: 1.6-12.4 IU/L

≥18 years

Premenopausal

Follicular: 2.1-10.9 IU/L

Midcycle: 20.0-100.0 IU/L

Luteal: 1.2-12.9 IU/L

Postmenopausal: 10.0-60.0 IU/L

 

TANNER STAGES*

Stage I: ≤2.0 IU/L

Stage II: ≤6.5 IU/L

Stage III: 0.3-17.2 IU/L

Stage IV: 0.5-26.3 IU/L

Stage V: 0.6-13.7 IU/L

*Puberty onset (transition from Tanner stage I to Tanner stage II) occurs for girls at a median age of 10.5 (± 2) years. There is evidence that it may occur up to 1 year earlier in obese girls and in African American girls. Progression through Tanner stages is variable. Tanner stage V (adult) should be reached by age 18.

 

Pediatric ranges derived for DXI method from analytic comparison to reference method in: Elmlinger MW, Kuhnel W, Ranke MB: Reference ranges for serum concentrations of lutropin (LH), follitropin (FSH), estradiol (E2), prolactin, progesterone, sex hormone-binding globulin (SHBG), dehydroepiandrosterone sulfate (DHEAS), cortisol and ferritin in neonates, children and young adults. Clin Chem Lab Med 2002;40(11):1151-1160

Day(s) and Time(s) Performed

Monday through Friday 5 a.m. – 12 a.m., Saturday 6 a.m. – 6 p.m.

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

83002

LOINC Code Information

Result ID Reporting Name LOINC Code
LH Luteinizing Hormone (LH), S 10501-5