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Test ID SGSU Synthetic Glucocorticoid Screen, Urine

Useful For

Confirming the presence of the listed synthetic glucocorticoids (see Interpretation)

 

Confirming the cause of secondary adrenal insufficiency

 

This assay does not detect fluticasone propionate.

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Stable Isotope Dilution Analysis

Reporting Name

Synthetic Glucocorticoid Screen, U

Specimen Type

Urine

Specimen Required

Container/Tube: Plastic, 10-mL urine tube (Supply T068)

Specimen Volume: 5 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative.

Specimen Minimum Volume

0.6 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Frozen (preferred) 14 days
  Ambient  7 days
  Refrigerated  7 days

Reference Values

Negative

Cutoff concentrations

Beclomethasone dipropionate: 0.10 mcg/dL

Betamethasone: 0.10 mcg/dL

Budesonide: 0.10 mcg/dL

Dexamethasone: 0.10 mcg/dL

Fludrocortisone: 0.10 mcg/dL

Flunisolide: 0.10 mcg/dL

Fluorometholone: 0.10 mcg/dL

Megestrol acetate: 0.10 mcg/dL

Methylprednisolone: 0.10 mcg/dL

Prednisolone: 0.10 mcg/dL

Prednisone: 0.10 mcg/dL

Triamcinolone 0.30 mcg/dL

Triamcinolone acetonide: 0.10 mcg/dL

 

Values for normal patients not taking these synthetic glucocorticoids should be less than the cutoff concentration (detection limit).

Day(s) and Time(s) Performed

Wednesday, 8 a.m.

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

82544

LOINC Code Information

Result ID Reporting Name LOINC Code
23561 Beclomethasone Dipropionate 46945-2
23562 Betamethasone 46946-0
23563 Budesonide 46947-8
23564 Dexamethasone 46948-6
23565 Fludrocortisone 46949-4
23566 Flunisolide 46950-2
23567 Fluorometholone 46951-0
23568 Fluticasone Propionate 46952-8
23569 Megestrol Acetate 46953-6
23570 Methylprednisolone 46954-4
23571 Prednisolone 46955-1
23572 Prednisone 46956-9
23573 Triamcinolone 46957-7
23574 Triamcinolone Acetonide 46958-5