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Test ID ALDEF Alpha Defensin, Lateral Flow Assay, Synovial Fluid

Ordering Guidance

This test should only be used for patients with a total joint prosthesis.

Necessary Information

Specimen source and type of joint are required. If not obtained from a prosthetic joint, testing will be canceled.


If ordering electronically, answers must be provided for the order entry questions.


If not ordering electronically, specimen source and type of joint must be provided on the request form.

Specimen Required

Collection Container/Tube: Plain red-top tube

Submission Container/Tube: Plastic vial

Specimen Volume: 0.6 mL

Useful For

Detection of alpha defensins 1-3, human host response proteins, in synovial fluid of adults with a total joint replacement who are being evaluated for revision surgery


This test is not intended to be used to determine timing for reimplantation in 2-stage procedures.

Method Name

Lateral Flow Assay (LFA)

Reporting Name

Alpha Defensin, Synovial Fluid, LFA

Specimen Type

Synovial Fluid

Specimen Minimum Volume

0.10 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Synovial Fluid Refrigerated 7 days

Reference Values


Reference values apply to all ages.

Day(s) Performed

Monday through Friday, Sunday

Report Available

Same day/1 day

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
ALDEF Alpha Defensin, Synovial Fluid, LFA 94718-4


Result ID Test Result Name Result LOINC Value
607711 Alpha Defensin, Synovial Fl, LFA 94718-4
JOINT Is this for a prosthetic joint? 86955-2
ADSRC Alpha Defensin Source 72923-6