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Test ID BHISC Bone Histomorphometry, Gross Microscopic Exam

Shipping Instructions

It is preferred that the specimen is shipped in 70% ethanol because it preserves the tetracycline label in the bone.

Necessary Information

Bone Histomorphometry: Patient Information (T352) in Special Instructions must be completed and sent with the specimen. The laboratory requires this information in order to perform testing.

Specimen Required


-Metal Free Specimen Vial (T173)

-Bone Histomorphometry Specimen Preparation (T579)

Specimen Type: Bone

Preferred: Anterior iliac crest

Container/Tube: Metal-free container (T173)

Specimen Volume: Entire specimen

Collection Instructions:

1. Fix specimen in 70% ethanol.

2. Quantitation of bone turnover requires 2 time-spaced tetracycline labels.

3. The use of metal-free containers is required to avoid aluminum or iron contamination.

Additional Information:

1. Consultation with a Mayo Clinic Laboratories pathologist or endocrinologist/nephrologist is recommended for first-time users of this service. Written instructions are available upon request.

2. For more information, see Bone Histomorphometry Specimen Preparation (T579) in Special Instructions.


Bone Histomorphometry: Patient Information (T352) in Special Instructions

Bone Histomorphometry Specimen Preparation (T579) in Special Instructions

Useful For

Undetermined metabolic bone disease in wet tissue specimens


Renal osteodystrophy






Paget disease


Assessing effects of therapy


Identification of some disorders of the hematopoietic system


Aluminum toxicity


Presence of iron in the bone

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
SS2PC SpecStain, Grp II, other No, (Bill Only) No

Testing Algorithm

Hematoxylin and eosin-stained slides are sent to pathology for review. Iron staining or aluminum staining may be performed at an additional charge.

Method Name


Reporting Name

Bone HistoMorph Gross Micro Exam

Specimen Type


Specimen Stability Information

Specimen Type Temperature Time Special Container
Varies Ambient (preferred)

Reference Values

The laboratory will provide a quantitative and an interpretive report.

Day(s) Performed

Monday through Friday

Report Available

26 to 35 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information




LOINC Code Information

Test ID Test Order Name Order LOINC Value
BHISC Bone HistoMorph Gross Micro Exam 60570-9


Result ID Test Result Name Result LOINC Value
71158 Interpretation 59465-5
71159 Bone Marrow Interpretation 51628-6
71160 Participated in the Interpretation No LOINC Needed
71161 Report electronically signed by 19139-5
71162 Material Received 22633-2
71786 Case Number 80398-1
601908 Disclaimer 62364-5