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Test ID CARU Cyclic Adenosine Monophosphate (cAMP), Urinary Excretion, Serum and Urine

Specimen Required

Both serum and urine are required. Serum must be obtained at the time of the urine collection.


Specimen Type: Serum


Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Serum gel tubes should be centrifuged within 2 hours of collection.

2. Red-top tubes should be centrifuged, and the serum aliquoted into a plastic vial within 2 hours of collection.

3. Label specimen as serum.


Specimen Type: Urine

Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Container/Tube: Plastic vial

Specimen Volume: 5 mL

Collection Instructions:

1. Collect a random urine specimen.

2. Label specimen as urine.

Useful For

Differential diagnosis of hypercalcemia


As an adjunct to serum parathyroid hormone measurements, especially in the diagnosis of parathyroid hormone resistance states, such as pseudohypoparathyroidism

Profile Information

Test ID Reporting Name Available Separately Always Performed
ACREA Creatinine, S Yes, (order CRTS1) Yes
CAMP Cyclic Amp, Urinary Excretion No Yes
CRETR Creatinine, Random, U Yes, (order RCTUR) Yes

Method Name

ACREA, CRETR: Enzymatic Colorimetric Assay

CAMP: Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Reporting Name

Cyclic Amp, Urinary Excretion

Specimen Type


Specimen Minimum Volume

Serum: 0.5 mL
Urine: 2.0 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 7 days
  Frozen  90 days
Urine Refrigerated (preferred) 28 days
  Frozen  28 days

Reference Values


1.3-3.7 nmol/dL of glomerular filtrate




0-11 months: 0.17-0.42 mg/dL

1-5 years: 0.19-0.49 mg/dL

6-10 years: 0.26-0.61 mg/dL

11-14 years: 0.35-0.86 mg/dL

≥15 years: 0.74-1.35 mg/dL



0-11 months: 0.17-0.42 mg/dL

1-5 years: 0.19-0.49 mg/dL

6-10 years: 0.26-0.61 mg/dL

11-15 years: 0.35-0.86 mg/dL

≥16 years: 0.59-1.04 mg/dL



No reference values apply. Interpret with other clinical data.

Day(s) Performed


Report Available

2 to 9 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information




LOINC Code Information

Test ID Test Order Name Order LOINC Value
CARU Cyclic Amp, Urinary Excretion 21052-6


Result ID Test Result Name Result LOINC Value
179 Cyclic Amp, Urinary Excretion 22712-4
ACREA Creatinine, S 2160-0
CRETR Creatinine, Random, U 2161-8