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Test ID CURCU Copper/Creatinine Ratio, Random, Urine

Specimen Required

Patient Preparation: High concentrations of barium are known to interfere with most metal tests. If barium-containing contrast media has been administered, a specimen should not be collected for at least 96 hours.

Supplies: Urine Tubes, 10 mL (T068)

Collection Container/Tube: Clean, plastic urine collection container with no metal cap or glued insert

Submission Container/Tube: Plastic, 10-mL urine tube or a clean, plastic aliquot container with no metal cap or glued insert

Specimen Volume: 3 mL

Collection Instructions:

1. Collect a random urine specimen.

2. See Metals Analysis Specimen Collection and Transport for complete instructions.

Useful For

Investigation of Wilson disease and obstructive liver disease using a random urine specimen

Profile Information

Test ID Reporting Name Available Separately Always Performed
CURC Copper/Creat Ratio, U No Yes
CRETR Creatinine, Random, U No Yes

Method Name

CURC: Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)

CRETR: Enzymatic Colorimetric Assay

Reporting Name

Copper/Creat Ratio, Random, U

Specimen Type


Specimen Minimum Volume

2 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  14 days

Reference Values



0-17 years: not established

≥18 years: 9-43 mcg/g creatinine


0-17 years: not established

≥18 years: 7-72 mcg/g creatinine



≥18 years old: 16-326 mg/dL

Reference values have not been established for patients who are less than 18 years of age.

Day(s) Performed

Monday, Thursday

Report Available

2 to 5 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information



LOINC Code Information

Test ID Test Order Name Order LOINC Value
CURCU Copper/Creat Ratio, Random, U 13829-7


Result ID Test Result Name Result LOINC Value
615258 Copper/Creat Ratio, U 13829-7
CRETR Creatinine, Random, U 2161-8