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Test ID EDN Eosinophil Derived Neurotoxin, Serum

Specimen Required

Supplies: Sarstedt Aliquot Tube, 5 mL (T914)


Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial within 12 hours of collection. Serum cannot sit on either gel or cells for longer than 12 hours.

Useful For

Evaluating patients suspected to have a condition associated with eosinophilia or hypereosinophilia


Evaluating patients with elevated peripheral blood eosinophil counts


Managing patients with elevated eosinophil-derived neurotoxin in the context of eosinophil-associated diseases

Method Name

Fluorescence Enzyme Immunoassay (FEIA)

Reporting Name

Eosinophil Derived Neurotoxin, S

Specimen Type


Specimen Minimum Volume

0.3 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 7 days
  Frozen  21 days

Reference Values

<70 mcg/L: Normal

70-99 mcg/L: Borderline

≥100 mcg/L: Elevated

Reference values apply to all ages.

Day(s) Performed


Report Available

2 to 8 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
EDN Eosinophil Derived Neurotoxin, S 100976-0


Result ID Test Result Name Result LOINC Value
EDN Eosinophil Derived Neurotoxin, S 100976-0