Sign in →

Test ID FACYS Acyclovir, Plasma

Specimen Required

Specimen Type: Plasma

Collection Container/Tube: Lavender top or pink top (EDTA)

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Draw blood in an EDTA (lavender top or pink top) tube(s). Plasma gel tube is not acceptable.

2. Centrifuge and send 1 mL of plasma refrigerated in a preservative-free plastic vial.

Method Name

High Performance Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

Reporting Name

Acyclovir, Plasma

Specimen Type

Plasma EDTA

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Plasma EDTA Refrigerated (preferred) 30 days
  Frozen  120 days
  Ambient  30 days

Reference Values

Reporting limit determined each analysis.


For using Acyclovir:

Usual therapeutic range (vs. Genital Herpes) during chronic oral daily divided dosages of 1200 - 2400 mg:

Peak: 0.40 - 2.0 mcg/mL plasma

Trough: 0.14 - 1.2 mcg/mL plasma


For using Valacyclovir as a metabolite:

Mean steady-state (± 1 SD) peak plasma levels following a 500 mg twice daily regimen

of Valacyclovir:

2.0-4.0 mcg Acyclovir/mL

Day(s) Performed

Monday - Sunday

Report Available

9 to 11 days

Performing Laboratory

NMS Labs

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
FACYS Acyclovir, Plasma 9416-9


Result ID Test Result Name Result LOINC Value
Z3531 Acyclovir Not Provided

Test Classification

This test was developed and its performance characteristics determined by NMS Labs. It has not been cleared or approved by the U.S. Food and Drug Administration.