Test ID FFCAH Congenital Adrenal Hyperplasia (CAH) Pediatric Profile 6, Comprehensive Screen
Specimen Required
Specimen Type: Serum
Container/Tube: Red
Specimen Volume: 3.5 mL
Collection Instructions: Draw blood in a plain, red-top tube(s). (Serum gel tube is not acceptable.) Spin down and separate within 1 hour of collection and send 3.5 mL of serum frozen in plastic vial.
Method Name
High Pressure Liquid Chromatography/Tandem Mass
Spectrometry (HPLC/MS-MS)
Reporting Name
CAH Profile 6Specimen Type
Serum RedSpecimen Minimum Volume
2 mL NOTE: Minimum volume does not allow for repeat analysis.
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Serum Red | Frozen | 90 days |
Reference Values
Androstenedione |
|
Units: ng/dL |
|
Age |
Range |
Premature (26-28w) Day 4 |
63 - 935 |
Premature (31-35w) Day 4 |
50 - 449 |
Full Term (1-7 days) |
<10 - 279 |
|
|
Levels decrease rapidly to <52 ng/dL after one week. |
|
|
|
1 - 11m |
<10 - 37 |
|
|
Androstenedione gradually decreases during the first six months to prepubertal levels. |
|
|
|
Prepubertal Children |
<10 - 17 |
Adult Males |
44 - 186 |
Adult Females |
28 - 230 |
Females Postmenopausal |
<10-93 |
Cortisol |
|
Units: ug/dL |
|
Age |
Range |
Premature (26-28w) Day 4 |
1.0 - 11 |
Premature (31-35w) Day 4 |
2.5 - 9.1 |
Full Term Day 3 |
1.7 - 14 |
Full Term Day 7 |
2.0 - 11 |
31d - 11m |
2.8 - 23 |
12m - 15y (8:00 AM) |
3 .0 - 21 |
|
|
Adults |
|
8:00 AM |
8.0 - 19 |
4:00 PM |
4.0 - 11 |
Deoxycorticosterone (DOC) |
|
Units: ng/dL |
|
Age |
Range |
Premature (26 - 28w) Day 4 |
20 - 105 |
Premature (34 - 36w) Day 4 |
28 - 78 |
|
|
Newborn: Levels are markedly elevated at birth and decrease rapidly during the first week to the range of 7 - 49 as found in older infants. |
|
|
|
1 - 11m |
7 - 49 |
Prepubertal Children |
2 - 34 |
Pubertal Children and Adults 8:00 AM |
2 - 19 |
Dehydroepiandrosterone (DHEA) |
|
Units: ng/dL |
|
Age |
Range |
Premature (26 - 31w) |
82 - 1484 |
Premature (32 - 35w) |
56 - 1853 |
Full Term (2 - 7d) |
41 - 1292 |
8d - 5m |
<948 |
6 - 12m |
<136 |
1 - 5 y |
<68 |
6 - 7 y |
<111 |
8 - 10 y |
<186 |
11 - 12 y |
<202 |
13 - 14 y |
<319 |
15 - 16 y |
39 - 481 |
17 - 19 y |
40 - 491 |
20 - 49 y |
31 - 701 |
≥ 50 y |
21 - 402 |
11-Desoxycortisol |
|
Units: ng/dL |
|
Age |
Range |
Premature (26-28w) Day 4 |
110 - 1376 |
Premature (31-35w) Day 4 |
48 - 579 |
Newborn Day 3 |
13 - 147 |
1 - 11m |
<10 - 156 |
Prepubertal 8:00 AM |
20 - 155 |
Pubertal Children and Adults 8:00 AM |
12 - 158 |
17-OH Pregnenolone |
|
Units: ng/dL |
|
Age |
Range |
Premature (26-28w) Day 4 |
375 - 3559 |
Premature (31-35w) Day 4 |
64 - 2380 |
3 Days |
10 - 829 |
1 - 5m |
36 - 763 |
6 - 11m |
42 - 540 |
12 - 23m |
14 - 207 |
24m - 5y |
10 - 103 |
6 - 9y |
10 - 186 |
Pubertal |
44 - 235 |
Adults |
53 - 357 |
Progesterone |
|
Units: ng/dL |
|
Males |
|
Age |
Range |
1 - 16y |
<10 - 15 |
Adults |
<10 - 11 |
|
|
Females |
|
Age |
Range |
1-10y |
<10 - 26 |
11y |
<10 - 255 |
12y |
<10 - 856 |
13y |
<10 - 693 |
14y |
<10 - 1204 |
15y |
<10 - 1076 |
16y |
<10 -1294 |
|
|
Adult |
|
Cycle Days |
Range |
1 - 6 |
<10 - 17 |
7 - 12 |
<10 - 135 |
13 - 15 |
<10 - 1563 |
16 - 28 |
<10 - 2555 |
Post Menopausal |
<10 |
|
|
Note: Luteal progesterone peaked from 350 to 3750 ng/dL on days ranging from 17 to 23. |
17-Alpha-Hydroxyprogesterone 17-OHP |
|
Units: ng/dL |
|
Age |
Range |
Premature (26-28w) Day 4 |
124 - 841 |
Premature (31-35w) Day 4 |
26 - 568 |
Full-Term Day 3 |
<78 |
|
|
Males: Levels increase after the first week to peak values ranging from 40 - 200 between 30 and 60 days. Values then decline to a prepubertal value of <91 before one year. |
|
|
|
Prepubertal |
<91 |
Adult Males |
27 - 199 |
|
|
Females |
|
1 - 11m |
13 - 106 |
Prepubertal |
<91 |
Adult Females |
|
Follicular |
15-70 |
Luteal |
35-290 |
Testosterone, Total |
|
|
|
Units: ng/dL |
|
|
|
Age |
Range |
|
|
Males |
|
|
|
Premature (26-28w) Day 4 |
59 - 125 |
|
|
Premature (31-35w) Day 4 |
37 - 198 |
|
|
Newborns |
75 - 400 |
|
|
|
|
|
|
1 - 7m: Levels decrease rapidly the first week to 20 - 50, then increase to 60 - 400 between 20 - 60 days. Levels then decline to prepubertal range levels of <2.5 - 10 by seven months. |
|||
|
|
|
|
Females |
|
|
|
Premature (26 - 28w) Day 4 |
5 - 16 |
|
|
Premature (31 - 35w) Day 4 |
5 - 22 |
|
|
Newborns |
20 - 64 |
|
|
|
|
|
|
1 - 7m: Levels decrease during the first month to less than 10 and remain there until puberty. |
|||
|
|
|
|
Prepubertal Males and Females |
<2.5 - 10 |
|
|
Adult Males >18 years |
264 - 916 |
|
|
Adult Females |
|
|
|
Premenopausal |
10 - 55 |
|
|
Postmenopausal |
7 - 40 |
|
|
|
|
|
|
Males |
|
|
|
Tanner Stage |
Age (years) |
Male |
|
1 |
<9.8 |
<2.5 - 10 |
|
2 |
9.8 - 14.5 |
18 - 150 |
|
3 |
10.7 - 15.4 |
100 - 320 |
|
4 |
11.8 - 16.2 |
200 - 620 |
|
5 |
12.8 - 17.3 |
350 - 970 |
|
|
|
|
|
Females |
|
|
|
Tanner Stage |
Age (years) |
Female |
|
1 |
<9.2 |
<2.5 - 10 |
|
2 |
9.2 - 13.7 |
7 - 28 |
|
3 |
10.0 - 14.4 |
15 - 35 |
|
4 |
10.7 - 15.6 |
13 - 32 |
|
5 |
11.8 - 18.6 |
20 - 38 |
|
Day(s) Performed
Monday, Wednesday
Report Available
10 to 19 daysPerforming Laboratory
Esoterix EndocrinologyCPT Code Information
82633/DOC
82634/ 11-Desoxycortisol
82157/Androstenedione
82533/Cortisol
82626/DHEA
84143/17-OH-Pregnenolone
84144/Progesterone
83498/17-OH-Progesterone
84403/Testosterone
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
FFCAH | CAH Profile 6 | Not Provided |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
Z5043 | Cortisol | 2143-6 |
Z5044 | Deoxycorticosterone (DOC) | 1656-8 |
Z5045 | 11-Desoxycortisol | 1657-6 |
Z5046 | Dehydroepiandrosterone (DHEA) | 2193-1 |
Z5047 | 17-OH Pregnenolone | 6765-2 |
Z5048 | Progesterone | 2839-9 |
Z5049 | 17-Alpha-Hydroxyprogesterone 17-OHP | 1668-3 |
Z5050 | Androstenedione | 1854-9 |
Z5051 | Testosterone, Total | 2986-8 |