Sign in →

Test ID FHLCA Immunoglobulin A (IgA) Heavy and Light Chain (HLC) Pairs, Kappa and Lambda with Ratio


Specimen Required


Specimen Type: Serum

Patient Preparation: Fasting: 8 hours

Collection Container/Tube:

Preferred: Red top

Acceptable: SST

Submission Container/Tube: Plastic vial

Specimen Volume: 0.75 mL

Collection Instructions:

1. Centrifuge immediately after coagulation (30 minutes) to prevent hemolysis.

2. Aliquot 0.75 mL of serum into a plastic vial.

3. Send refrigerated


Useful For

For the quantitative measurement of human IgA heavy chain and light chain intact immunoglobulin in serum. The result can be used when monitoring previously diagnosed IgA multiple myeloma patients and is used in conjunction with other clinical and laboratory findings.

 

Heavy and light chain pair quantitation may be useful for:

1. Distinguishing between broadly migrating monoclonal proteins and restricted polyclonal immunoglobulin patterns on serum protein electrophoresis.

2. Quantitating monoclonal IgA proteins that are difficult to quantitate using serum protein electrophoresis alone.

3. Providing a more specific quantitation of the monoclonal protein than total IgA measurements alone.

Reporting Name

IgA Heavy Light Chains (HLC), S

Specimen Type

Serum

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 14 days
  Ambient  14 days
  Frozen  14 days

Reference Values

IgA Kappa (g/L): 0.48-2.82

IgA Lambda (g/L): 0.36-1.98

IgA Kappa:IgA Lambda ratio: 0.80-2.04

Day(s) Performed

Tuesday, Friday

Report Available

1 to 9 days

Performing Laboratory

LabCorp Burlington

CPT Code Information

83883 x 2

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FHLCA IgA Heavy Light Chains (HLC), S 74773-3

 

Result ID Test Result Name Result LOINC Value
Z5616 IgA Kappa, S 74864-0
Z5617 IgA Lambda, S 74865-7
Z5618 IgA K/L HLC Ratio 74869-9

Method Name

Turbidimetric