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Test ID HBBSN Hepatitis B Surface Antibody Screen, Qualitative/Quantitative, Serum

Ordering Guidance

If patient is being monitored for hepatitis B immune globulin (HBIG) therapy after organ transplantation, order HBABT / Hepatitis B Surface Antibody Monitor, Post-Transplant, Serum.


This test should not be used for prenatal screening of pregnant individuals with or without risk factors for hepatitis B virus (HBV) infection. For testing such, order HBABP / Hepatitis B Surface Antibody Prenatal, Qualitative/Quantitative, Serum.


This test should not be used for diagnostic testing of symptomatic individuals to evaluate post-vaccination immunity status or post-acute infection status of HBV. For testing such patients, order HBAB / Hepatitis B Surface Antibody, Qualitative/Quantitative, Serum.

Necessary Information

Date of collection is required.

Specimen Required

Collection Container/Tube: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Centrifuge blood collection tube per collection tube manufacturer's instructions (eg, centrifuge and aliquot within 2 hours of collection for BD Vacutainer tubes).

2. Aliquot serum into plastic vial.

Useful For

Identifying previous exposure to hepatitis B virus

Method Name

Chemiluminescent Immunoassay (CIA)

Reporting Name

HBs Antibody Scrn, S

Specimen Type

Serum SST

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum SST Frozen (preferred) 28 days
  Refrigerated  7 days
  Ambient  24 hours

Reference Values


Unvaccinated: Negative

Vaccinated: Positive



Unvaccinated: <5.0 mIU/mL

Vaccinated: ≥12.0 mIU/mL


See Viral Hepatitis Serologic Profiles

Day(s) Performed

Monday through Saturday

Report Available

Same day/1 to 3 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information


G0499 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
HBBSN HBs Antibody Scrn, S 5193-8


Result ID Test Result Name Result LOINC Value
HBASN HBs Antibody Scrn, S 10900-9
HBSQN HBs Antibody, Quantitative, S 5193-8


If not ordering electronically, complete, print, and send 1 of the following:

-Gastroenterology and Hepatology Client Test Request (T728)

-Infectious Disease Serology Test Request (T916)