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Test ID HEVQU Hepatitis E Virus RNA Detection and Quantification, Real-Time RT-PCR, Serum

Shipping Instructions

1. Freeze serum immediately, and ship specimen frozen on dry ice.

2. If shipment will be delayed for more 24 hours, freeze serum at -20 to -80° C (up to 35 days) until shipment on dry ice.

Specimen Required

Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 1.8 mL

Collection Instructions:

1. Centrifuge blood collection tube per collection tube manufacturer's instructions (eg, centrifuge within 2 hours of collection for BD Vacutainer tubes).

2. Aliquot serum into plastic vial.

Useful For

Virologic detection and confirmation of hepatitis E virus (HEV) infection in individuals who are immunocompromised and are at risk for or suspected to have acute or chronic hepatitis E


Monitoring HEV RNA levels and determining eradication of chronic HEV infection in individuals who are immunocompromised

Testing Algorithm

For more information see Hepatitis E: Testing Algorithm for Diagnosis and Management.

Method Name

Real-Time Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR)

Reporting Name

HEV RNA Detect / Quant, S

Specimen Type

Serum SST

Specimen Minimum Volume

0.8 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum SST Frozen (preferred) 35 days ALIQUOT TUBE
  Refrigerated  5 days ALIQUOT TUBE

Reference Values


Day(s) Performed


Report Available

1 to 10 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
HEVQU HEV RNA Detect / Quant, S 69961-1


Result ID Test Result Name Result LOINC Value
62929 HEV RNA Detect / Quant, S 69961-1


If not ordering electronically, complete, print, and send 1 of the following with the specimen:

-Gastroenterology and Hepatology Client Test Request (T728)

-Microbiology Test Request (T732)