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HelpTest ID HMUCR Heavy Metal/Creatinine Ratio, with Reflex, Random, Urine
Specimen Required
Patient Preparation:
-Patient should not eat seafood for a 48-hour period prior to start of collection.
-High concentrations of gadolinium and iodine are known to interfere with most metal tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.
Supplies: Urine Tubes, 10 mL (T068)
Collection Container/Tube: Clean, plastic urine container with no metal cap or glued insert
Submission Container/Tube: Plastic, 10-mL urine tube or clean, plastic aliquot container with no metal cap or glued insert
Specimen Volume: 6 mL
Collection Instructions:
1. Collect a random urine specimen.
2. See Trace Metals Analysis Specimen Collection and Transport for complete instructions.
Useful For
Preferred screening test for detection of arsenic, cadmium, mercury, and lead in random urine specimens
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| ASCU | Arsenic/Creatinine Ratio, U | Yes, (order ASUCR) | Yes |
| CDCU | Cadmium/Creatinine Ratio, U | Yes, (order CDUCR) | Yes |
| HGCU | Mercury/Creatinine Ratio, U | Yes, (order HGUCR) | Yes |
| PBCU | Lead/Creatinine Ratio, U | Yes, (order PBUCR) | Yes |
| CRETR | Creatinine, Random, U | No | Yes |
Reflex Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| SPAS | Arsenic Speciation, Random, U | Yes | No |
Testing Algorithm
If the total arsenic concentration is 10 mcg/L or greater, then speciation will be performed at an additional charge.
For more information see Porphyria (Acute) Testing Algorithm
Special Instructions
Method Name
ASCU, CDCU, HGCU, PBCU: Triple Quadrupole Inductively Coupled Plasma Mass Spectrometry (ICP-MS/MS)
CRETR: Enzymatic Colorimetric Assay
Reporting Name
Heavy Metal/Creat Ratio,w/Reflex,USpecimen Type
UrineSpecimen Minimum Volume
3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Urine | Refrigerated (preferred) | 7 days | |
| Frozen | 7 days |
Reference Values
ARSENIC/CREATININE:
≥18 years: <24 mcg/g creatinine
CADMIUM/CREATININE:
≥18 years: <0.6 mcg/g creatinine
MERCURY/CREATININE:
≥18 years: <2 mcg/g creatinine
LEAD/CREATININE:
≥18 years: <2 mcg/g creatinine
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
82175
82300
83825
83655
82570
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| HMUCR | Heavy Metal/Creat Ratio,w/Reflex,U | 29589-9 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 608902 | Cadmium/Creatinine Ratio, U | 13471-8 |
| 608903 | Mercury/Creatinine Ratio, U | 13465-0 |
| 608904 | Lead/Creatinine Ratio, U | 13466-8 |
| CRETR | Creatinine, Random, U | 2161-8 |
| 608900 | Arsenic/Creatinine Ratio, U | 13463-5 |
| 608901 | Total Arsenic Concentration | 5586-3 |
Day(s) Performed
Monday through Friday