Sign in →

Test ID HMUOE Heavy Metal Occupational Exposure, with Reflex, Random, Urine

Specimen Required

Patient Preparation:

1. Patient should not eat seafood for a 48-hour period prior to start of collection.

2. High concentrations of gadolinium and iodine are known to interfere with most metal tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.

Supplies: Urine Tubes, 10 mL (T068)

Collection Container/Tube: Clean, plastic urine container with no metal cap or glued insert

Submission Container/Tube: Plastic, 10-mL urine tube or clean, plastic aliquot container with no metal cap or glued insert

Specimen Volume: 6 mL

Collection Instructions:

1. Collect a random urine specimen.

2. See Trace Metals Analysis Specimen Collection and Transport for complete instructions.

Useful For

Preferred screening test for detection of arsenic, cadmium, mercury, and lead due to occupational exposure using random urine specimens

Profile Information

Test ID Reporting Name Available Separately Always Performed
ASOU Arsenic Occupational Exposure Yes, (order ASUOE) Yes
CDOU Cadmium Occupational Exposure Yes, (order CDUOE) Yes
HGOU Mercury Occupational Exposure Yes, (order HGUOE) Yes
PBOU Lead Occupational Exposure Yes, (order PBOUE) Yes
CRETR Creatinine, Random, U No Yes

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
SPAS Arsenic Speciation, Random, U Yes No

Testing Algorithm

If arsenic concentration is greater than or equal to 10 mcg/L, then speciation will be performed at an additional charge.

Method Name

ASOU, CDOU, HGOU, PBOU: Triple Quadrupole Inductively Coupled Plasma-Mass Spectrometry (ICP-MS/MS)

CRETR: Enzymatic Colorimetric Assay

Reporting Name

Heavy Metal Occ Exp w/Reflex, U

Specimen Type


Specimen Minimum Volume

3 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 7 days
  Frozen  7 days

Reference Values


Biological Exposure Indices (BEI): <35 mcg/L at end of work week



BEI: <5.0 mcg/g creatinine



BEI: <35 mcg/g creatinine



BEI: <150 mcg/g creatinine

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information






LOINC Code Information

Test ID Test Order Name Order LOINC Value
HMUOE Heavy Metal Occ Exp w/Reflex, U 29589-9


Result ID Test Result Name Result LOINC Value
CRETR Creatinine, Random, U 2161-8
608890 Arsenic Occupational Exposure 13463-5
608892 Cadmium Occupational Exposure 13471-8
608893 Mercury Occupational Exposure 13465-0
608894 Lead Occupational Exposure 13466-8
608891 Total Arsenic Concentration 5586-3

Day(s) Performed

Monday through Friday

Report Available

2 to 4 days