Home
HelpTest ID HSCHP High Sensitivity Clonal Hematopoiesis Panel, Next-Generation Sequencing, Blood
Ordering Guidance
This test is not a prenatal screening test. For prenatal screening, consider QUAD1 / Quad Screen (Second Trimester) Maternal, Serum.
Multiple oncology (cancer) gene panels are available. For more information see Hematology, Oncology, and Hereditary Test Selection Guide.
Specimen Required
Patient Preparation: A previous hematopoietic stem cell transplant from an allogenic donor will interfere with testing. For information about testing patients who have received a hematopoietic stem cell transplant, call 800-533-1710.
Specimen Type: Whole blood
Container/Tube: Lavender top (EDTA) or yellow top (ACD)
Specimen Volume: 3 mL
Collection Instructions:
1. Invert several times to mix blood.
2. Send whole blood specimen in original tube. Do not aliquot.
3. Whole blood collected postnatal from an umbilical cord is also acceptable. See Additional Information
Specimen Stability Information: Ambient (preferred) 4 days/Refrigerated 4 days/Frozen 4 days
Additional Information:
1. Specimens are preferred to be received within 4 days of collection. Extraction will be attempted for specimens received after 4 days, and DNA yield will be evaluated to determine if testing may proceed.
2. To ensure minimum volume and concentration of DNA are met, the requested volume must be submitted. Testing may be canceled if DNA requirements are inadequate.
3. For postnatal umbilical cord whole blood specimens, maternal cell contamination studies are recommended to ensure test results reflect that of the patient tested. A maternal blood specimen is required to complete maternal cell contamination studies. Order MATCC / Maternal Cell Contamination, Molecular Analysis, Varies on both the cord blood and maternal blood specimens under separate order numbers.
Useful For
Evaluating clonal hematopoiesis (CH) prior to initiation of genotoxic therapy
Monitoring clonal evolution and the emergence of clinically relevant clones throughout the course of genotoxic treatment
Distinguishing tumor driver mutations from CH-associated variants
Method Name
Targeted Next-Generation Sequencing (NGS)
Reporting Name
HS Clonal Hematopoiesis PanelSpecimen Type
VariesSpecimen Minimum Volume
See Specimen Required
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Varies | Ambient (preferred) | |
| Frozen | ||
| Refrigerated | ||
Reference Values
An interpretive report will be provided.
Day(s) Performed
Varies
Report Available
9 to 15 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
81479
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| HSCHP | HS Clonal Hematopoiesis Panel | In Process |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 623138 | Result | 82939-0 |
| 623139 | Interpretation | 69047-9 |
| 623140 | Additional Information | 48767-8 |
| 623141 | Specimen | 31208-2 |
| 623142 | Method | 85069-3 |
| 623143 | Disclaimer | 62364-5 |
| 623670 | Released By | 18771-6 |