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Test ID IBDP2 Inflammatory Bowel Disease Serology Panel, Serum

Specimen Required

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.

Useful For

Distinguishing between ulcerative colitis and Crohn disease in patients for whom the specific diagnosis is unclear based on endoscopic, pathologic, and imaging evaluations


This test is not useful for determining the extent of disease in patients with inflammatory bowel disease or determining the response to disease-specific therapy including surgical resection of diseased intestine.

Profile Information

Test ID Reporting Name Available Separately Always Performed
ANCA2 Cytoplasmic Neutrophilic Ab IBD, S No Yes
SCERA Saccharomyces cerevisiae Ab, IgA, S Yes Yes
SCERG Saccharomyces cerevisiae Ab, IgG, S Yes Yes

Method Name

SCERA, SCERG: Enzyme-Linked Immunosorbent Assay (ELISA)

ANCA2: Indirect Immunofluorescent Assay (IFA)

Reporting Name

Inflammatory Bowel Disease Panel, S

Specimen Type


Specimen Minimum Volume

0.8 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 21 days
  Frozen  21 days

Reference Values

Saccharomyces cerevisiae ANTIBODY, IgA

Negative: <20.0 RU/mL

Positive: ≥20.0 RU/mL


Saccharomyces cerevisiae ANTIBODY, IgG

Negative: <20.0 RU/mL

Positive: ≥20.0 RU/mL



Negative (not detectable)

Day(s) Performed

Monday through Friday

Report Available

3 to 7 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

86671 x 2


LOINC Code Information

Test ID Test Order Name Order LOINC Value
IBDP2 Inflammatory Bowel Disease Panel, S 87551-8


Result ID Test Result Name Result LOINC Value
610030 Cytoplasmic Neutrophilic Ab IBD, S 17355-9
SCERA Saccharomyces cerevisiae Ab, IgA, S 47320-7
SCERG Saccharomyces cerevisiae Ab, IgG, S 47321-5
614542 ANCA2 Interpretation 49308-0


If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

-Gastroenterology and Hepatology Client Test Request (T728)