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HelpTest ID KRASD Cell-Free DNA KRAS 12, 13, 61,146, Blood
Ordering Guidance
This test is not a prenatal screening test. To evaluate for the presence of common fetal chromosome abnormalities using cell-free DNA, order NIPS / Cell-Free DNA Prenatal Screen.
Shipping Instructions
1. Samples should be transported at ambient temperature or refrigerated (4° C).
2. Samples are viable for 7 days in the Streck Black/Tan Top Tube Kit (T715).
Specimen Required
Supplies: Streck Black/Tan Top Tube Kit (T715)
Container/Tube: Streck Cell-Free DNA blood collection kit (T715)
Specimen Volume: Two 10-mL Streck Cell-Free DNA blood collection tubes
Additional Information: Only blood collected in Streck Cell-Free DNA BCT tubes will be accepted for analysis. Whole blood will be processed to produce platelet-poor plasma before cfDNA isolation.
Useful For
As an alternative to invasive tissue biopsies for the determination of KRAS 12, 13, 61,146 (G12A, G12C, G12D, G12R, G12S, G12V, G13D, Q61K, Q61L, Q61R, Q61H, and A146T) mutation status
Selection of patients with colorectal cancer who are most likely to benefit from epidermal growth factor receptor (EGFR)-targeted therapies
Method Name
Digital Droplet Polymerase Chain Reaction (PCR)
Reporting Name
cfDNA KRAS 12, 13, 61, 146 BloodSpecimen Type
Whole bloodSpecimen Minimum Volume
One 10 mL Streck tube
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Whole blood | Ambient (preferred) | 7 days | Streck Black/Tan top |
| Refrigerated | 7 days | Streck Black/Tan top |
Day(s) Performed
Monday through Friday
Report Available
5 to 10 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
81275
81276
81479 (if appropriate for government payers)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| KRASD | cfDNA KRAS 12, 13, 61, 146 Blood | In Process |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 113123 | Result Summary | 50397-9 |
| 113508 | Result | 75974-6 |
| 113125 | Interpretation | 69047-9 |
| 113126 | Additional Information | 48767-8 |
| 113127 | Specimen | 31208-2 |
| 113128 | Source | 31208-2 |
| 113129 | Released By | 18771-6 |
Forms
If not ordering electronically, complete, print, and send an Oncology Test Request (T729) with the specimen.