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Test ID OAUS Organic Acids Screen, Urine Spot

Ordering Guidance

The preferred screening test for organic acidemias is OAU / Organic Acids Screen, Random, Urine, which should be ordered unless collecting and/or sending urine is difficult or not feasible.

Necessary Information

1. Patient's age is required.

2. Biochemical Genetics Patient Information (T602) is recommended, but not required, to be filled out and sent with the specimen to aid in the interpretation of test results.

Specimen Required

Supplies: Card-Blood Spot Collection (Filter Paper) (T493)

Collection Container:

Preferred: Blood Spot Collection Card

Acceptable: Whatman Protein Saver 903 paper, PerkinElmer 226 (formerly Ahlstrom 226) filter paper, Munktell filter paper

Specimen Volume: 1 Filter paper card soaked with urine, typically requires 2 to 3 mL of urine

Collection Instructions

1. Soak a filter paper card with urine, approximately 22 cm(2) in area (typically requires 2 to 3 mL of urine; exact measurement is not important as urine volume will be normalized to creatinine). Note: Filter paper sample may be collected by dipping the card into a collection cup of urine. Avoid dilute urine if possible.

2. Let urine dry on filter paper at ambient temperature in a horizontal position for a minimum of 3 hours.

3. Do not expose specimen to heat or direct sunlight.

4. Do not stack wet specimens.

5. Keep specimen dry.

Useful For

Diagnosis of inborn errors of metabolism using dried urine specimens

Method Name

Gas Chromatography Mass Spectrometry (GC-MS)

Reporting Name

Organic Acids Scrn, US

Specimen Type


Specimen Minimum Volume

2 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Frozen (preferred) 28 days FILTER PAPER
  Ambient  14 days FILTER PAPER
  Refrigerated  14 days FILTER PAPER

Reference Values

An interpretive report will be provided.

Day(s) Performed

Monday through Saturday

Report Available

3 to 5 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
OAUS Organic Acids Scrn, US 49287-6


Result ID Test Result Name Result LOINC Value
610707 Organic Acids Scrn, US 49287-6


1. Biochemical Genetics Patient Information (T602)

2. If not ordering electronically, complete, print, and send a Biochemical Genetics Test Request (T798) with the specimen.