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Test ID PDCRW Pompe Disease Cross-Reactive Immunological Material Status, Leukocytes

Shipping Instructions

For optimal isolation of leukocytes, it is recommended the specimen arrive refrigerated within 7 days of collection to be stabilized. Collect specimen Monday through Thursday only and not the day before a holiday. Specimen should be collected and packaged as close to shipping time as possible.

Specimen Required

Supplies: Vacutainer 4.0 mL CPT Sodium Citrate Mononuclear Cell Preparation, 4.0 mL (T840)

Container/Tube: Sodium citrate cell preparation tube (CPT blue/black striped top)

Specimen Volume: 4 mL

Collection Instructions:

1. Collect 4 mL blood in CPT mononuclear, sodium citrate CPT tube (blue/black striped top)

2. Mix by inversion 6 to 8 times.

3. Centrifuge at 1800xg for 30 minutes within 2 hours of collection.

4. Send CPT tube on cold packs. Do not aliquot plasma.

Useful For

Determination of cross-reactive immunologic material status using leukocytes from patients with Pompe disease


Evaluating the best strategy for enzyme replacement therapy for patients with Pompe disease

Testing Algorithm

For more information see Newborn Screen Follow-up for Pompe Disease

Method Name

Western Blot

Reporting Name

Pompe Disease CRIM Status, WBC

Specimen Type

Whole blood

Specimen Minimum Volume

2 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Whole blood Refrigerated 7 days NaCit BLUBLK CellPrep

Reference Values

An interpretive report will be provided

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
PDCRW Pompe Disease CRIM Status, WBC 99308-9


Result ID Test Result Name Result LOINC Value
606127 GAA CRIM status In Process
606128 Interpretation 59462-2
606129 Reviewed By 18771-6

Day(s) Performed

Once per month

For patients 6 months of age or younger at collection, sample will be run as soon as received in lab. For patients older than 6 months of age at collection, samples will be batched and ran once per month.

Report Available

4 to 45 days