Test ID PK1 Pyruvate Kinase Enzyme Activity, Blood
Specimen Required
Collection Container/Tube:
Preferred: Yellow top (ACD solution B)
Acceptable: Lavender top (EDTA)
Specimen Volume: 6 mL
Collection Instructions: Send specimen in original tube. Do not transfer blood to other containers.
Useful For
Evaluation of nonspherocytic hemolytic anemia
Evaluation of neonatal anemia or jaundice
Evaluation of unexplained noninfectious hepatic failure
Evaluation of unexplained iron overload
Evaluation of unusually severe hemoglobin S trait
Evaluation of unusually severe glucose 6-phosphate dehydrogenase deficiency
Investigating families with pyruvate kinase deficiency to determine inheritance pattern and for genetic counseling
Method Name
Kinetic Spectrophotometry
Reporting Name
PK Enzyme Activity, BSpecimen Type
Whole Blood ACD-BSpecimen Minimum Volume
1 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Whole Blood ACD-B | Refrigerated | 20 days |
Reference Values
≥12 months of age: 5.5-12.4 U/g Hb
Reference values have not been established for patients who are less than12 months of age.
Performing Laboratory

Test Classification
This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
84220
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
PK1 | PK Enzyme Activity, B | 32552-2 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
PKCL | PK Enzyme Activity, B | 32552-2 |
Day(s) Performed
Monday through Friday
Report Available
1 to 4 daysForms
If not ordering electronically, complete, print, and send a Benign Hematology Test Request (T755) with the specimen.