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Test ID PLFA Cryptococcus Antigen Screen, Lateral Flow Assay, Pleural Fluid

Additional Testing Requirements

Pleural fluid testing for cryptococcal antigen should also be submitted for routine fungal culture. Order FGEN / Fungal Culture, Routine.

Specimen Required

Container/Tube: Sterile vial

Specimen Volume: 0.5 mL

Useful For

Diagnosis of infection with Cryptococcus species

Testing Algorithm

If this screen is positive, the antigen titer will be performed at an additional charge.

Method Name

Lateral Flow Assay (LFA)

Reporting Name

Cryptococcus Ag Screen, LFA, PF

Specimen Type

Pleural Fluid

Specimen Minimum Volume


Specimen Stability Information

Specimen Type Temperature Time Special Container
Pleural Fluid Refrigerated (preferred) 21 days
  Frozen  30 days

Reference Values


Day(s) Performed

Monday through Sunday

Report Available

Same day/1 to 2 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

87899-Cryptococcus Ag Screen, LFA, PF

87899-Cryptococcus Ag Titer, LFA, PF (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
PLFA Cryptococcus Ag Screen, LFA, PF 29533-7


Result ID Test Result Name Result LOINC Value
42396 Cryptococcus Ag Screen, LFA, PF 29533-7

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
PLFAT Cryptococcus Ag Titer, LFA, PF No No


If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.