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Test ID PLP Pyridoxal 5-Phosphate, Plasma

Useful For

Determining vitamin B6 status, including in persons who present with progressive nerve compression disorders, such as carpal tunnel and tarsal tunnel syndromes

 

Determining the overall success of a vitamin B6 supplementation program

 

Diagnosis and evaluation of hypophosphatasia

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Reporting Name

Pyridoxal 5-Phosphate (PLP), P

Specimen Type

Plasma Heparin


Shipping Instructions


Ship specimen in amber vial to protect from light.



Specimen Required


Patient Preparation:

1. Patient should fast overnight (12-14 hours); infants-should have specimen collected before next feeding. Water can be taken as needed.

2. For 24 hours before specimen collection, patient should not take multivitamins or vitamin supplements.

Supplies: Amber Frosted Tube, 5 mL (T915)

Collection Container/Tube:

Preferred: Green top (sodium or lithium heparin) or Plasma gel separator (PST)

Acceptable: None

Submission Container/Tube: Amber vial

Specimen Volume: 1 mL

Collection Instructions:

1. Within 2 hours of collection, centrifuge at 4° C.

2. Aliquot all plasma into amber vial and freeze immediately.


Specimen Minimum Volume

0.75 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Plasma Heparin Frozen 29 days LIGHT PROTECTED

Reference Values

5-50 mcg/L

Day(s) Performed

Monday through Thursday, Saturday, Sunday

Report Available

2 to 7 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

84207

LOINC Code Information

Test ID Test Order Name Order LOINC Value
PLP Pyridoxal 5-Phosphate (PLP), P 30552-4

 

Result ID Test Result Name Result LOINC Value
4047 Pyridoxal 5-Phosphate (PLP), P 30552-4

Forms

If not ordering electronically, complete, print, and send a General Request (T239) with the specimen.