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Test ID POWV Powassan Virus, IgM, Enzyme-Linked Immunosorbent Assay, Serum

Ordering Guidance

For patients with less than 7 days of symptoms, the recommended testing is molecular analysis for detection of Powassan virus (POWV) RNA. Contact either a local Public Health Laboratory or the Centers for Disease Control and Prevention.

Specimen Required

Supplies: Sarstedt 5 mL Aliquot Tube (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.6 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.

Useful For

Diagnosis of Powassan virus infection.


This test should not be used as a screening procedure for the general population.


This test should not be used as a "test of cure."

Method Name

Enzyme-Linked Immunosorbent Assay (ELISA)

Reporting Name

Powassan Virus, IgM, ELISA, S

Specimen Type


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 14 days
  Frozen  30 days

Reference Values


Reference values apply to all ages.

Day(s) Performed

Tuesday, Thursday

Report Available

Same day/1 to 4 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
POWV Powassan Virus, IgM, ELISA, S 29855-4


Result ID Test Result Name Result LOINC Value
POWV Powassan Virus, IgM, ELISA, S 29855-4


If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.