Test ID SNTX N-terminal Telopeptide, Serum
Specimen Required
Patient Preparation: Fasting is preferred due to diurnal variation of markers and food effects.
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions:
1. A morning collection from fasting patients is preferred. If not possible, collect the baseline and subsequent specimens under the same circumstances (eg, at same time of day).
2. Centrifuge and aliquot serum into a plastic vial.
Useful For
Monitoring effectiveness of antiresorptive therapy in patients treated for osteoporosis or other metabolic bone disorders
As an adjunct in the diagnosis of medical conditions associated with increased bone turnover
This test is not useful for screening or diagnosing osteoporosis.
Method Name
Enzyme-Linked Immunosorbent Assay (ELISA)
Reporting Name
NTX-Telopeptide, SSpecimen Type
SerumSpecimen Minimum Volume
0.1 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Serum | Frozen (preferred) | 28 days | |
Refrigerated | 24 hours |
Reference Values
All units are reported in nmol bone collagen equivalents (BCE)
Adult (≥18 years of age)
Males:
5.4-24.2 nmol BCE
Females:
Premenopausal: 6.2-19.0 nmol BCE
The target value for postmenopausal adult females undergoing treatment for osteoporosis is the same as the premenopausal reference interval.
Day(s) Performed
Monday, Thursday
Report Available
2 to 5 daysPerforming Laboratory

Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
82523
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
SNTX | NTX-Telopeptide, S | 21215-9 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
65558 | NTX-Telopeptide, S | 21215-9 |