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Test ID SUP24 Supersaturation Profile, 24 Hour, Urine


Ordering Guidance


X-ray dyes and contrast media will affect uric acid test results.

-If a kidney X-ray with dye or computerized tomography (CT) scan with contrast has been performed, patient should wait a minimum of 1 day before starting collection.

-If a cholangiography (bile duct X-ray) has performed, patient should wait 7 days before starting collection.

-Urine must be collected before tablets have been taken for gallbladder X-ray, otherwise patient should wait 7 days before starting collection.



Necessary Information


1. 24-Hour volume is required.

2. Patient's height in centimeters and weight in kilograms are required if patient is younger than 18 years.



Specimen Required


Supplies: Diazolidinyl Urea (Germall) 5.0 mL (T822)

Collection Container/Tube: 24-hour graduated urine container with no metal cap or glued insert

Submission Container/Tube: Plastic, 60-mL urine bottle

Specimen Volume: 35 mL

Collection Instructions:

1. Collect urine for 24 hours.

2. Add 5 mL of diazolidinyl urea as preservative at start of collection or refrigerate specimen during and after collection.

3. Specimen pH should be between 4.5 and 8 and will stay in this range if kept refrigerated. Specimens with pH above 8 indicate bacterial contamination, and testing will be canceled. Do not attempt to adjust pH as it will adversely affect results.

Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens for multiple collections.


Useful For

Diagnosis and management of patients with renal lithiasis:

-Predicting the likely composition of the stone, in patients who have a radiopaque stone, for whom stone analysis is not available. This may help in designing a treatment program.

 

Aiding in identification of specific risk factors for stones using a 24-hour urine collection

 

Monitoring the effectiveness of therapy by confirming that the crystallization potential has indeed decreased

 

Evaluating kidney excretion of acid and urine pH

 

Estimating a patient's protein intake

Profile Information

Test ID Reporting Name Available Separately Always Performed
SSINT Supersaturation, 24 HR, U 1 No Yes
NAUT Sodium, 24 HR, U Yes, (order NAU) Yes
KUT Potassium, 24 HR, U Yes, (order KUR) Yes
CALUT Calcium, 24 HR, U Yes, (order CALU) Yes
MAGT Magnesium, 24 HR, U Yes, (order MAGU) Yes
CLUT Chloride, 24 HR, U Yes, (order CLU) Yes
POUT Phosphorus, 24 HR, U Yes, (order POU) Yes
SULFT Sulfate, 24 HR, U Yes, (order SULFU) Yes
CITT Citrate Excretion, 24 HR, U Yes, (order CITR) Yes
OXUT Oxalate, 24 HR, U Yes, (order OXU) Yes
UPHT pH, 24 HR, U Yes, (order PHU_) Yes
URICT Uric Acid, 24 HR, U Yes, (order URCU) Yes
CTUT Creatinine, 24 HR, U Yes, (order URCU) Yes
OSMUT Osmolality, 24 HR, U Yes, (order UOSMU) Yes
AMMT Ammonium, 24 HR, U Yes, (order AMMO) Yes
UNT Urea Nitrogen, 24 HR, U No Yes
PCRUT Protein Catabolic Rate, 24 HR, U No Yes
DEMO9 Patient Demographics No Yes

Method Name

AMMT, CITT, OXUT: Enzymatic

OSMUT: Freezing Point Depression

SULFT: High-Performance Ion Chromatography (HPIC)

CALUT, POUT: Photometric

MAGT: Colorimetric Endpoint Assay

UPHT: pH Meter

NAUT, KUT, CLUT: Potentiometric, Indirect Ion-Selective Electrode (ISE)

CTUT: Enzymatic Colorimetric Assay

URICT: Uricase

UNT: Kinetic UV Assay

PCRUT, SSINT: Calculation

Reporting Name

Supersaturation, 24 HR, U

Specimen Type

Urine

Specimen Minimum Volume

25 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated 14 days

Reference Values

SUPERSATURATION REFERENCE MEANS (Delta G: DG)

Calcium oxalate: 1.77 DG

Brushite: 0.21 DG

Hydroxyapatite: 3.96 DG

Uric acid: 1.04 DG

 

INDIVIDUAL URINE ANALYTES

 

OSMOLALITY, 24 HOUR, URINE

0-11 months: 50-750 mOsm/kg

≥12 months: 150-1,150 mOsm/kg

 

pH, 24 HOUR, URINE

4.5-8.0

 

SODIUM, 24 HOUR, URINE

≥18 years: 22-328 mmol/24 hours

Reference values have not been established for patients who are less than 18 years of age.

 

POTASSIUM, 24 HOUR, URINE

≥18 years: 16-105 mmol/24 hours

Reference values have not been established for patients who are less than 18 years of age.

 

CALCIUM, 24 HOUR, URINE

Males: <250 mg/24 hours

Females: <200 mg/24 hours

Reference values have not been established for patients who are less than 18 years of age.

 

MAGNESIUM, 24 HOUR, URINE

51-269 mg/24 hours

Reference values have not been established for patients who are younger than 18 years of age.

 

CHLORIDE, 24 HOUR, URINE

≥18 years: 34-286 mmol/24 hours

Reference values have not been established for patients who are younger than 18 years of age.

 

PHOSPHORUS, 24 HOUR, URINE

≥18 years: 226-1,797 mg/24hours

Reference values have not been established for patients who are less younger 18 years of age.

 

SULFATE, 24 HOUR, URINE

7-47 mmol/24 hours

 

CITRATE EXCRETION, 24 HOUR, URINE

0-19 years: Not established

20 years: 150-1,191 mg/24 hours

21 years: 157-1,191 mg/24 hours

22 years: 164-1,191 mg/24 hours

23 years: 171-1,191 mg/24 hours

24 years: 178-1,191 mg/24 hours

25 years: 186-1,191 mg/24 hours

26 years: 193-1,191 mg/24 hours

27 years: 200-1,191 mg/24 hours

28 years: 207-1,191 mg/24 hours

29 years: 214-1,191 mg/24 hours

30 years: 221-1,191 mg/24 hours

31 years: 228-1,191 mg/24 hours

32 years: 235-1,191 mg/24 hours

33 years: 242-1,191 mg/24 hours

34 years: 250-1,191 mg/24 hours

35 years: 257-1,191 mg/24 hours

36 years: 264-1,191 mg/24 hours

37 years: 271-1,191 mg/24 hours

38 years: 278-1,191 mg/24 hours

39 years: 285-1,191 mg/24 hours

40 years: 292-1,191 mg/24 hours

41 years: 299-1,191 mg/24 hours

42 years: 306-1,191 mg/24 hours

43 years: 314-1,191 mg/24 hours

44 years: 321-1,191 mg/24 hours

45 years: 328-1,191 mg/24 hours

46 years: 335-1,191 mg/24 hours

47 years: 342-1,191 mg/24 hours

48 years: 349-1,191 mg/24 hours

49 years: 356-1,191 mg/24 hours

50 years: 363-1,191 mg/24 hours

51 years: 370-1,191 mg/24 hours

52 years: 378-1,191 mg/24 hours

53 years: 385-1,191 mg/24 hours

54 years: 392-1,191 mg/24 hours

55 years: 399-1,191 mg/24 hours

56 years: 406-1,191 mg/24 hours

57 years: 413-1,191 mg/24 hours

58 years: 420-1,191 mg/24 hours

59 years: 427-1,191 mg/24 hours

60 years: 434-1,191 mg/24 hours

>60 years: Not established

 

OXALATE, 24 HOUR, URINE

0.11-0.46 mmol/24 hours

9.7-40.5 mg/24 hours

 

Reference values have not been established for patients who are younger than 16 years of age.

 

URIC ACID, 24 HOUR, URINE

Males: ≥18 years: 200-1,000 mg/24 hours

Females: ≥18 years: 250-750 mg/24 hours

Reference values have not been established for patients who are younger than 18 years of age.

 

CREATININE, 24 HOUR, URINE

Males: ≥18 years: 930-2,955 mg/24 hours

Females: ≥18 years: 603-1,783 mg/24 hours

Reference values have not been established for patients who are younger than 18 years of age.

 

AMMONIUM, 24 HOUR, URINE

15-56 mmol/24 hour

Reference values have not been established for patients who are younger than 18 years or older than 77 years of age.

 

UREA NITROGEN, 24 HOUR, URINE

≥18 years: 7-42 g/24h

Reference values have not been established for patients who are younger than 18 years of age.

 

PROTEIN CATABOLIC RATE, 24 HOUR, URINE

56-125 g/24 hours

Day(s) Performed

Monday through Friday

Report Available

2 to 5 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

82340-Calcium

82436-Chloride

82507-Citrate excretion

82570-Creatinine

83735-Magnesium

83935-Osmolality

83945-Oxalate

83986-pH

84105-Phosphorus

84133-Potassium

84300-Sodium

84392-Sulfate

84560-Uric acid

82140-Ammonium

84540-Urea Nitrogen

LOINC Code Information

Test ID Test Order Name Order LOINC Value
SUP24 Supersaturation, 24 HR, U 81232-1

 

Result ID Test Result Name Result LOINC Value
CRU24 Creatinine, 24 HR, U 2162-6
AMU24 Ammonium, 24 HR, U 25308-8
CAU24 Calcium, 24 HR, U 6874-2
CIT24 Citrate Excretion, 24 HR, U 6687-8
CLU24 Chloride, 24 HR, U 2079-2
KU24 Potassium, 24 HR, U 2829-0
MGU24 Magnesium, 24 HR, U 24447-5
NAU24 Sodium, 24 HR, U 2956-1
UOSMT Osmolality, 24 HR, U 2694-8
PCRUT Protein Catabolic Rate, 24 HR, U 93746-6
POU24 Phosphorus, 24 HR, U 2779-7
SUL24 Sulfate, 24 HR, U 26889-6
UNU24 Urea Nitrogen, 24 HR, U 3096-5
UPHT pH, 24 HR, U 27378-9
URC24 Uric Acid, 24 HR, U 3087-4
616217 Calcium Oxalate Crystal 81623-1
BSA1 Patient Surface Area 8277-6
OXM24 Oxalate, 24 HR, U (mmol/24 HR) 14862-7
OXG24 Oxalate, 24 HR, U (mg/24 HR) 2701-1
HT6 Height (cm) 3137-7
616218 Brushite Crystal 101825-8
616219 Hydroxyapatite Crystal 81622-3
WT6 Weight (kg) 29463-7
616220 Uric Acid Crystal 101827-4
SSDUR Collection Duration 13362-9
SSVOL Volume 3167-4
21060 Interpretation 69051-1

Urine Preservative Collection Options

Note: The addition of preservative or application of temperature controls must occur at the beginning of the collection.

Ambient

No

Refrigerate

OK

Frozen

No

50% Acetic Acid

No

Boric Acid

No

Diazolidinyl Urea

Preferred

6M Hydrochloric Acid

No

6M Nitric Acid

No

Sodium Carbonate

No

Thymol

No

Toluene

No