Sign in →

Test ID SUPRA Supersaturation Profile, Random, Urine

Ordering Guidance

A timed 24-hour urine collection is the preferred specimen for measuring and interpreting this profile to determine kidney stone risk factors (SUP24 / Supersaturation Profile, 24 Hour, Urine). Random urine collections with individual analytes normalized to urinary creatinine may be of some clinical use in patients who cannot collect a 24-hour specimen, typically small children. Therefore, this test is offered on random collections for children less than 16 years old.


X-ray dyes and contrast media will affect uric acid test results.

-If a kidney X-ray with dye or computerized tomography (CT) scan with contrast has been performed, patient should wait a minimum of 1 day before starting collection.

-If a cholangiography (bile duct X-ray) has performed, patient should wait 7 days before starting collection.

-Urine must be collected before tablets have been taken for gallbladder X-ray, otherwise patient should wait 7 days before starting collection.

Necessary Information

Patient's age is required.

Specimen Required


-Urine Tubes, 10 mL (T068)

-Sarstedt Aliquot Tube, 5 mL (T914)

Container/Tube: 2 Plastic, 10-mL urine tubes and 5 plastic, 5-mL tubes

Specimen Volume: 40 mL

Collection Instructions:

1. Collect a random urine specimen and divide the urine into 7 tubes.

2. Refrigerate specimen after collection. Specimen pH should be between 4.5 and 8 and will stay in this range if kept refrigerated. Specimens with pH above 8 indicate bacterial contamination, and testing will be canceled. Do not attempt to adjust pH as it will adversely affect results.

Useful For

Diagnosis and management of patients with renal lithiasis:

-Predicting the likely composition of the stone, in patients who have a radiopaque stone, for whom stone analysis is not available. This may help in designing a treatment program

-Identifying specific risk factors for stones formation using a random urine collection

-Monitoring the effectiveness of therapy by confirming that the crystallization potential has indeed decreased

-Evaluation of kidney excretion of acid and urine pH

Profile Information

Test ID Reporting Name Available Separately Always Performed
SRINT Supersaturation, Random, U 1 No Yes
RANAU Sodium, Random, U Yes, (order RNAUR) Yes
RAKUR Potassium, Random, U Yes, (order RKUR) Yes
RACAL Calcium, Random, U Yes, (order CACR3) Yes
RAMAG Magnesium, Random, U Yes, (order MAGRU) Yes
RACLU Chloride, Random, U Yes, (order RCHLU) Yes
RAPOU Phosphorus, Random, U Yes, (order RPHOC) Yes
RASUL Sulfate, Random, U No Yes
RACIT Citrate Excretion, Random, U Yes, (order CITRA) Yes
RAOXU Oxalate, Random, U Yes, (order ROXUR) Yes
RAPHU pH, Random, U No Yes
RAURA Uric Acid, Random, U Yes, (order RURC1) Yes
RACTU Creatinine, Random, U Yes, (order RCTUR) Yes
RAOSM Osmolality, Random, U No Yes
RAAMM Ammonium, Random, U Yes, (order RAMBO) Yes

Method Name


RAOSM: Freezing Point Depression

RASUL: High-Performance Ion Chromatography (HPIC)

RAMAG: Colorimetric Endpoint Assay

RACAL, RAPOU: Photometric

RAPHU: pH Meter

RANAU, RAKUR, RACLU: Potentiometric, Indirect Ion-Selective Electrode (ISE)

RACTU: Enzymatic Colorimetric Assay

RAURA: Uricase

Reporting Name

Supersaturation, Random, U

Specimen Type


Specimen Minimum Volume

30 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated 14 days

Reference Values

The following analytes do not have any established reference values:

Sodium, potassium, chloride, phosphorus, citrate, sulfate, and oxalate

pH: 4.5-8.0



≥18 years old: 16-326 mg/dL

Reference values have not been established for patients who are <18 years of age.



0-11 months: 50-750 mOsm/kg

≥12 months: 150-1,150 mOsm/kg



18-77 years: 3-65 mmol/L

No reference values established for patients who are younger than 18 years or older than 77 years of age



1 month-<12 months: 0.03-0.81 mg/mg creat

12 months-<24 months: 0.03-0.56 mg/mg creat

24 months-<3 years: 0.02-0.50 mg/mg creat

3 years-<5 years: 0.02-0.41 mg/mg creat

5 years-<7 years: 0.01-0.30 mg/mg creat

7 years-<10 years: 0.01-0.25 mg/mg creat

10 years-<18 years: 0.01-0.24 mg/mg creat

18 years-83 years: 0.05-0.27 mg/mg creat

Reference values have not been established for patients who are younger than 1 month of age or older than 83 years of age.



Magnesium/Creatinine Ratio:

1 month-<12 months: 0.10-0.48 mg/mg creat

12 months-<24 months: 0.09-0.37 mg/mg creat

24 months-<3 years: 0.07-0.34 mg/mg creat

3 years-<5 years: 0.07-0.29 mg/mg creat

5 years-<7 years: 0.06-0.21 mg/mg creat

7 years-<10 years: 0.05-0.18 mg/mg creat

10 years-<14 years: 0.05-0.15 mg/mg creat

14 years-<18 years: 0.05-0.13 mg/mg creat

18 years-83 years: 0.04-0.12 mg/mg creat

Reference values have not been established for patients who are younger than 1 month of age or older than 83 years of age.

Day(s) Performed

Monday through Friday

Report Available

2 to 5 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information



82507-Citrate excretion










84560-Uric acid


LOINC Code Information

Test ID Test Order Name Order LOINC Value
SUPRA Supersaturation, Random, U 101929-8


Result ID Test Result Name Result LOINC Value
RASUC Sulfate, Random, U 2975-1
RAPHU pH, Random, U 2756-5
RAOSU Osmolality, Random, U 2695-5
RANAC Sodium, Random, U 2955-3
RACTU Creatinine, Random, U 2161-8
RAKUC Potassium, Random, U 2828-2
RACLC Chloride, Random, U 2078-4
RAAMM Ammonium, Random, U 1842-4
RACAC Calcium, Random, U 17862-4
CITCO Citrate Excretion, Random, U 2128-7
RAMGC Magnesium, Random, U 19124-7
POUCO Phosphorus, Random, U 2778-9
RAUAC Uric Acid, Random, U 3086-6
OXMCO Oxalate, Random, U (mmol/L) 15086-2
616399 Calcium Oxalate Crystal In Process
616400 Brushite Crystal In Process
OXGCO Oxalate, Random, U (mg/L) 2700-3
UACCR Uric Acid/Creat Ratio, Random, U 3089-0
PHOCR Phosphorus/Creat Ratio, Random, U 11141-9
MAGCR Magnesium/Creat Ratio, Random, U 13474-2
CITCR Citrate/Creatinine Ratio, Random, U 13722-4
CALCR Calcium/Creatinine Ratio, Random, U 9321-1
OXUCR Oxalate/Creatinine Ratio, Random, U 13483-3
616401 Hydroxyapatite Crystal In Process
616402 Uric Acid Crystal In Process
616403 Sodium Urate Crystal In Process
31246 Interpretation 69051-1