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HelpTest ID TACPK Tacrolimus, Peak, Blood
Useful For
Assessment of postdosing (peak) blood tacrolimus concentrations
Method Name
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Reporting Name
Tacrolimus, Peak, BSpecimen Type
Whole Blood EDTANecessary Information
Date of last dose, time of last dose, and dosage information are required.
Specimen Required
Container/Tube: Lavender top (EDTA)
Specimen Volume: 3 mL
Collection Instructions:
1. Do not centrifuge.
2. Send whole blood specimen in original tube. Do not aliquot.
Specimen Minimum Volume
1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Whole Blood EDTA | Refrigerated (preferred) | 14 days | |
| Ambient | 14 days | ||
| Frozen | 14 days |
Reference Values
5.0-30.0 ng/mL
Target steady-state trough concentrations vary depending on the type of transplant, concomitant immunosuppression, clinical/institutional protocols, and time posttransplant. Results should be interpreted in conjunction with this clinical information and any physical signs or symptoms of rejection or toxicity.
Day(s) Performed
Monday through Sunday
Report Available
2 to 4 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
80197
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| TACPK | Tacrolimus, Peak, B | 59822-7 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 88157 | Tacrolimus, Peak, B | 59822-7 |
| DAT7 | Date of last dose | 29742-4 |
| TM01 | Time of last dose | 29637-6 |
| DOSE1 | Dose, mg | 32594-4 |
Forms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.