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Test ID TSPU Targeted Stimulant Screen, Random, Urine

Additional Testing Requirements

In most cases, no additional testing is needed after the qualitative targeted stimulant test is performed if the parent drug or metabolites found are consistent with the patients prescribed medications. However, if unexpected stimulant is found, confirmatory testing can be requested at an additional charge.

Specimen Required

Supplies: Sarstedt 5 mL Aliquot Tube (T914)

Collection Container/Tube: Plastic urine container

Submission Container/Tube: Plastic, 5-mL tube

Specimen Volume: 1 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative

Useful For

Determining compliance or identifying illicit stimulant drug use


This test is not intended for employment-related testing.

Profile Information

Test ID Reporting Name Available Separately Always Performed
LPPS List prescribed stimulants No Yes
TSTIM Targeted Stimulant Screen, U No Yes

Method Name

Liquid Chromatography-Tandem Mass Spectrometry, High Resolution Accurate Mass (LC-MS/MS HRAM)

Reporting Name

Targeted Stimulant Screen, U

Specimen Type


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 14 days
  Frozen  28 days

Reference Values

Not detected


Cutoff concentrations:

Methamphetamine: 100 ng/mL

Amphetamines: 100 ng/mL

3,4-Methylenedioxymethamphetamine (MDMA): 100 ng/mL

3,4-Methylenedioxy-N-ethylamphetamine (MDEA): 100 ng/mL

3,4-Methylenedioxyamphetamine (MDA): 100 ng/mL

Ephedrine: 100 ng/mL

Pseudoephedrine: 100 ng/mL

Phentermine: 100 ng/mL

Phencyclidine (PCP): 20 ng/mL

Methylphenidate: 20 ng/mL

Ritalinic acid: 100 ng/mL

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information


G0480 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
TSPU Targeted Stimulant Screen, U 99107-5


Result ID Test Result Name Result LOINC Value
610273 Methamphetamine 19554-5
LPPS List prescribed stimulants 29305-0
610274 Amphetamine 19343-3
610275 3,4-methylenedioxymethamphetamine (MDMA) 19568-5
610276 3,4-methylenedioxy-N-ethylamphetamine (MDEA) 59844-1
610277 3,4-methylenedioxyamphetamine (MDA) 19565-1
610278 Ephedrine 99108-3
610279 Pseudoephedrine 99109-1
610280 Phentermine 19674-1
610281 Phencyclidine (PCP) 19659-2
610282 Methylphenidate 19577-6
610283 Ritalinic acid 99110-9
610284 Stimulant Interpretation 54247-2

Day(s) Performed

Monday through Saturday

Report Available

3 to 4 days


If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.